Optimal timing of a γH2AX analysis to predict cellular lethal damage in cultured tumor cell lines after exposure to diagnostic and therapeutic radiation doses

Phosphorylated H2AX (γH2AX) is a sensitive biomarker of DNA double-strand breaks (DSBs). To assess the adverse effects of low-dose radiation (<50 mGy), γH2AX levels have typically been measured in human lymphocytes within 30 min of computed tomography (CT) examinations. However, in the presence o...

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Detalles Bibliográficos
Autores principales: Takano, Seiya, Shibamoto, Yuta, Wang, Zhen, Kondo, Takuhito, Hashimoto, Shingo, Kawai, Tatsuya, Hiwatashi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036098/
https://www.ncbi.nlm.nih.gov/pubmed/36634337
http://dx.doi.org/10.1093/jrr/rrac096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036098/
https://www.ncbi.nlm.nih.gov/pubmed/36634337
http://dx.doi.org/10.1093/jrr/rrac096

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