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The impact of TP53 status of tumor cells including the type and the concentration of administered (10)B delivery agents on compound biological effectiveness in boron neutron capture therapy

Human head and neck squamous cell carcinoma cells transfected with mutant TP53 (SAS/mp53) or neo vector (SAS/neo) were inoculated subcutaneously into left hind legs of nude mice. After the subcutaneous administration of a (10)B-carrier, boronophenylalanine-(10)B (BPA) or sodium mercaptododecaborate-...

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Detalles Bibliográficos
Autores principales: Masunaga, Shin-ichiro, Sanada, Yu, Takata, Takushi, Tanaka, Hiroki, Sakurai, Yoshinori, Suzuki, Minoru, Kirihata, Mitsunori, Ono, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036103/
https://www.ncbi.nlm.nih.gov/pubmed/36763853
http://dx.doi.org/10.1093/jrr/rrad001