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The impact of TP53 status of tumor cells including the type and the concentration of administered (10)B delivery agents on compound biological effectiveness in boron neutron capture therapy
Human head and neck squamous cell carcinoma cells transfected with mutant TP53 (SAS/mp53) or neo vector (SAS/neo) were inoculated subcutaneously into left hind legs of nude mice. After the subcutaneous administration of a (10)B-carrier, boronophenylalanine-(10)B (BPA) or sodium mercaptododecaborate-...
Autores principales: | Masunaga, Shin-ichiro, Sanada, Yu, Takata, Takushi, Tanaka, Hiroki, Sakurai, Yoshinori, Suzuki, Minoru, Kirihata, Mitsunori, Ono, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036103/ https://www.ncbi.nlm.nih.gov/pubmed/36763853 http://dx.doi.org/10.1093/jrr/rrad001 |
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