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Analysis of the relationship between LET, γH2AX foci volume and cell killing effect of carbon ions using high-resolution imaging technology

The strong cell killing effect of high linear energy transfer (LET) carbon ions is dependent on lethal DNA damage. Our recent studies suggest that induction of clusters of double-strand breaks (DSBs) in close proximity is one of the potential mechanisms. However, the relationship between LET, the de...

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Detalles Bibliográficos
Autores principales: Oike, Takahiro, Kakoti, Sangeeta, Sakai, Makoto, Matsumura, Akihiko, Ohno, Tatsuya, Shibata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036109/
https://www.ncbi.nlm.nih.gov/pubmed/36621883
http://dx.doi.org/10.1093/jrr/rrac098