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Analysis of the relationship between LET, γH2AX foci volume and cell killing effect of carbon ions using high-resolution imaging technology
The strong cell killing effect of high linear energy transfer (LET) carbon ions is dependent on lethal DNA damage. Our recent studies suggest that induction of clusters of double-strand breaks (DSBs) in close proximity is one of the potential mechanisms. However, the relationship between LET, the de...
Autores principales: | Oike, Takahiro, Kakoti, Sangeeta, Sakai, Makoto, Matsumura, Akihiko, Ohno, Tatsuya, Shibata, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036109/ https://www.ncbi.nlm.nih.gov/pubmed/36621883 http://dx.doi.org/10.1093/jrr/rrac098 |
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