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Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein

Infections with Chikungunya virus, a mosquito-borne alphavirus, cause an acute febrile syndrome often followed by chronic arthritis that persists for months to years post-infection. Neutralizing antibodies are the primary immune correlate of protection elicited by infection, and the major goal of va...

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Detalles Bibliográficos
Autores principales: Powers, John M., Lyski, Zoe L., Weber, Whitney C., Denton, Michael, Streblow, Magdalene M., Mayo, Adam T., Haese, Nicole N., Nix, Chad D., Rodríguez-Santiago, Rachel, Alvarado, Luisa I., Rivera-Amill, Vanessa, Messer, William B., Streblow, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036167/
https://www.ncbi.nlm.nih.gov/pubmed/36913428
http://dx.doi.org/10.1371/journal.pntd.0011154