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Prediction model for milk transfer of drugs by primarily evaluating the area under the curve using QSAR/QSPR

PURPOSE: Information on milk transferability of drugs is important for patients who wish to breastfeed. The purpose of this study is to develop a prediction model for milk-to-plasma drug concentration ratio based on area under the curve (M/P(AUC)). The quantitative structure–activity/property relati...

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Detalles Bibliográficos
Autores principales: Maeshima, Tae, Yoshida, Shin, Watanabe, Machiko, Itagaki, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036427/
https://www.ncbi.nlm.nih.gov/pubmed/36720832
http://dx.doi.org/10.1007/s11095-023-03477-1