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Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters

ABCG46 of the legume Medicago truncatula is an ABC-type transporter responsible for highly selective translocation of the phenylpropanoids, 4-coumarate, and liquiritigenin, over the plasma membrane. To investigate molecular determinants of the observed substrate selectivity, we applied a combination...

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Detalles Bibliográficos
Autores principales: Pakuła, Konrad, Sequeiros-Borja, Carlos, Biała-Leonhard, Wanda, Pawela, Aleksandra, Banasiak, Joanna, Bailly, Aurélien, Radom, Marcin, Geisler, Markus, Brezovsky, Jan, Jasiński, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036432/
https://www.ncbi.nlm.nih.gov/pubmed/36952129
http://dx.doi.org/10.1007/s00018-023-04751-6