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Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters
ABCG46 of the legume Medicago truncatula is an ABC-type transporter responsible for highly selective translocation of the phenylpropanoids, 4-coumarate, and liquiritigenin, over the plasma membrane. To investigate molecular determinants of the observed substrate selectivity, we applied a combination...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036432/ https://www.ncbi.nlm.nih.gov/pubmed/36952129 http://dx.doi.org/10.1007/s00018-023-04751-6 |