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Highly-sensitive label-free deep profiling of N-glycans released from biomedically-relevant samples
Alterations of protein glycosylation can serve as sensitive and specific disease biomarkers. Labeling procedures for improved separation and detectability of oligosaccharides have several drawbacks, including incomplete derivatization, side-products, noticeable desialylation/defucosylation, sample l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036494/ https://www.ncbi.nlm.nih.gov/pubmed/36959283 http://dx.doi.org/10.1038/s41467-023-37365-4 |