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Highly-sensitive label-free deep profiling of N-glycans released from biomedically-relevant samples

Alterations of protein glycosylation can serve as sensitive and specific disease biomarkers. Labeling procedures for improved separation and detectability of oligosaccharides have several drawbacks, including incomplete derivatization, side-products, noticeable desialylation/defucosylation, sample l...

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Detalles Bibliográficos
Autores principales: Marie, Anne-Lise, Ray, Somak, Ivanov, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036494/
https://www.ncbi.nlm.nih.gov/pubmed/36959283
http://dx.doi.org/10.1038/s41467-023-37365-4