Combining machine learning and structure-based approaches to develop oncogene PIM kinase inhibitors

Introduction: PIM kinases are targets for therapeutic intervention since they are associated with a number of malignancies by boosting cell survival and proliferation. Over the past years, the rate of new PIM inhibitors discovery has increased significantly, however, new generation of potent molecul...

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Detalles Bibliográficos
Autores principales: Almukadi, Haifa, Jadkarim, Gada Ali, Mohammed, Arif, Almansouri, Majid, Sultana, Nasreen, Shaik, Noor Ahmad, Banaganapalli, Babajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036574/
https://www.ncbi.nlm.nih.gov/pubmed/36970406
http://dx.doi.org/10.3389/fchem.2023.1137444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036574/
https://www.ncbi.nlm.nih.gov/pubmed/36970406
http://dx.doi.org/10.3389/fchem.2023.1137444

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