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Combining machine learning and structure-based approaches to develop oncogene PIM kinase inhibitors
Introduction: PIM kinases are targets for therapeutic intervention since they are associated with a number of malignancies by boosting cell survival and proliferation. Over the past years, the rate of new PIM inhibitors discovery has increased significantly, however, new generation of potent molecul...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036574/ https://www.ncbi.nlm.nih.gov/pubmed/36970406 http://dx.doi.org/10.3389/fchem.2023.1137444 |