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Integrating RNA-seq and scRNA-seq to explore the mechanism of macrophage ferroptosis associated with COPD

Aims: Our study focused on whether macrophages ferroptosis is associated with the pathogenesis of chronic obstructive pulmonary disease (COPD) or not. Main methods: We first identified macrophage module genes by weighted gene co-expression network analysis (WGCNA) in RNA sequencing (RNA-seq) date fr...

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Detalles Bibliográficos
Autores principales: Fan, Pengbei, Zhang, Yige, Ding, Shenao, Du, Zhixin, Zhou, Chunyu, Du, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036582/
https://www.ncbi.nlm.nih.gov/pubmed/36969832
http://dx.doi.org/10.3389/fphar.2023.1139137