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Ferric quinate (QPLEX) inhibits the interaction of major outer membrane protein (MOMP) with the Lewis b (Le(b)) antigen and limits Campylobacter colonization in broilers

Campylobacter jejuni colonizes hosts by interacting with Blood Group Antigens (BgAgs) on the surface of gastrointestinal epithelia. Genetic variations in BgAg expression affects host susceptibility to C. jejuni. Here, we show that the essential major outer membrane protein (MOMP) of C. jejuni NCTC11...

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Detalles Bibliográficos
Autores principales: Okoye, Jennifer C., Holland, Alexandria, Pitoulias, Matthaios, Paschalis, Vasileios, Piddubnyi, Artem, Dufailu, Osman A., Borén, Thomas, Oldfield, Neil J., Mahdavi, Jafar, Soultanas, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036597/
https://www.ncbi.nlm.nih.gov/pubmed/36970690
http://dx.doi.org/10.3389/fmicb.2023.1146418