Molecular simulations of SSTR2 dynamics and interaction with ligands

The cyclic peptide hormone somatostatin regulates physiological processes involved in growth and metabolism, through its binding to G-protein coupled somatostatin receptors. The isoform 2 (SSTR2) is of particular relevance for the therapy of neuroendocrine tumours for which different analogues to so...

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Detalles Bibliográficos
Autores principales: Gervasoni, Silvia, Guccione, Camilla, Fanti, Viviana, Bosin, Andrea, Cappellini, Giancarlo, Golosio, Bruno, Ruggerone, Paolo, Malloci, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036620/
https://www.ncbi.nlm.nih.gov/pubmed/36959237
http://dx.doi.org/10.1038/s41598-023-31823-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036620/
https://www.ncbi.nlm.nih.gov/pubmed/36959237
http://dx.doi.org/10.1038/s41598-023-31823-1

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