Orally disintegrating tablets containing famotidine nanoparticles provide high intestinal absorbability via the energy-dependent endocytosis pathway

The permeability of the Biopharmaceutics Classification System (BCS) class III drugs are low, and their oral bioavailability needs to be improved. In this study, we attempted to design oral formulations containing famotidine (FAM) nanoparticles to overcome the limitations of BCS class III drugs. Dis...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Ogata, Fumihiko, Kadowaki, Reita, Deguchi, Saori, Otake, Hiroko, Nakazawa, Yosuke, Nagata, Mayumi, Sasaki, Hiroshi, Kawasaki, Naohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036753/
https://www.ncbi.nlm.nih.gov/pubmed/36970629
http://dx.doi.org/10.3389/fbioe.2023.1167291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036753/
https://www.ncbi.nlm.nih.gov/pubmed/36970629
http://dx.doi.org/10.3389/fbioe.2023.1167291

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