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Efficient isolation of rare B cells using next-generation antigen barcoding

The ability to efficiently isolate antigen-specific B cells in high throughput will greatly accelerate the discovery of therapeutic monoclonal antibodies (mAbs) and catalyze rational vaccine development. Traditional mAb discovery is a costly and labor-intensive process, although recent advances in s...

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Detalles Bibliográficos
Autores principales: Hurtado, Jonathan, Flynn, Claudia, Lee, Jeong Hyun, Salcedo, Eugenia C., Cottrell, Christopher A., Skog, Patrick D., Burton, Dennis R., Nemazee, David, Schief, William R., Landais, Elise, Sok, Devin, Briney, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036767/
https://www.ncbi.nlm.nih.gov/pubmed/36968243
http://dx.doi.org/10.3389/fcimb.2022.962945