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Culture density influences the functional phenotype of human macrophages

Macrophages (MΦ) are commonly cultured in vitro as a model of their biology and functions in tissues. Recent evidence suggests MΦ to engage in quorum sensing, adapting their functions in response to cues about the proximity of neighboring cells. However, culture density is frequently overlooked in t...

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Detalles Bibliográficos
Autores principales: Ruder, Adele V., Temmerman, Lieve, van Dommelen, Joep M.A., Nagenborg, Jan, Lu, Chang, Sluimer, Judith C., Goossens, Pieter, Biessen, Erik A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036771/
https://www.ncbi.nlm.nih.gov/pubmed/36969194
http://dx.doi.org/10.3389/fimmu.2023.1078591