Sodium butyrate supresses malignant human mast cell proliferation, downregulates expression of KIT and promotes differentiation

Sodium butyrate (NaBu) is a class I histone deacetylase inhibitor (HDACi) that can impede the proliferation of transformed cells. Although some HDACi downregulate the expression of the stem cell factor receptor (KIT/CD117), the effect of NaBu on KIT expression and human mast cell proliferation requi...

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Detalles Bibliográficos
Autores principales: MacDonald, Clayton A., Qian, Hui, Pundir, Priyanka, Kulka, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Allergy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036836/
https://www.ncbi.nlm.nih.gov/pubmed/36970068
http://dx.doi.org/10.3389/falgy.2023.1109717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036836/
https://www.ncbi.nlm.nih.gov/pubmed/36970068
http://dx.doi.org/10.3389/falgy.2023.1109717

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