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Sodium butyrate supresses malignant human mast cell proliferation, downregulates expression of KIT and promotes differentiation
Sodium butyrate (NaBu) is a class I histone deacetylase inhibitor (HDACi) that can impede the proliferation of transformed cells. Although some HDACi downregulate the expression of the stem cell factor receptor (KIT/CD117), the effect of NaBu on KIT expression and human mast cell proliferation requi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036836/ https://www.ncbi.nlm.nih.gov/pubmed/36970068 http://dx.doi.org/10.3389/falgy.2023.1109717 |