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Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment

INTRODUCTION: Adipocytes in the tumour microenvironment are highly dynamic cells that have an established role in tumour progression, but their impact on anti-cancer therapy resistance is becoming increasingly difficult to overlook. METHODS: We investigated the role of adipose tissue and adipocytes...

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Detalles Bibliográficos
Autores principales: Surendran, Abera, Jamalkhah, Monire, Poutou, Joanna, Birtch, Rayanna, Lawson, Christine, Dave, Jaahnavi, Crupi, Mathieu J. F., Mayer, Justin, Taylor, Victoria, Petryk, Julia, de Souza, Christiano Tanese, Moodie, Neil, Billingsley, Jacob Lecompte, Austin, Bradley, Cormack, Nicole, Blamey, Natalie, Rezaei, Reza, McCloskey, Curtis W., Fekete, Emily E. F., Birdi, Harsimrat K., Neault, Serge, Jamieson, Taylor R., Wylie, Brenna, Tucker, Sarah, Azad, Taha, Vanderhyden, Barbara, Tai, Lee-Hwa, Bell, John C., Ilkow, Carolina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036842/
https://www.ncbi.nlm.nih.gov/pubmed/36969187
http://dx.doi.org/10.3389/fimmu.2023.1099459