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BALB.NCT-Cpox(nct) is a unique mouse model of hereditary coproporphyria

In humans, mutations in the coproporphyrinogen oxidase (CPOX) gene can result in hereditary coproporphyria (HCP), characterized by high levels of coproporphyrin excretion in the urine and feces, as well as acute neurovisceral and chronic cutaneous manifestations. Appropriate animal models for compre...

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Detalles Bibliográficos
Autores principales: Kang, Xiaojing, Shimada, Shin, Miyahara, Hiroki, Higuchi, Keiichi, Mori, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036863/
https://www.ncbi.nlm.nih.gov/pubmed/36967721
http://dx.doi.org/10.1016/j.ymgmr.2023.100964