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Case of cryptic TNIP1::PDGFRB rearrangement presenting with myelodysplastic syndrome achieved hematologic and cytogenetic remission with low-dose imatinib plus decitabine therapy

For a long time, FIP1L1::PDGFRA fusion seems to be the only cryptic rearrangement of myeloid/lymphoid neoplasm with tyrosine kinase gene fusions. Recently, with the wide application of RNA sequencing, more cryptic rearrangements of other TK genes have been identified, especially the PDGFRB. Here we...

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Detalles Bibliográficos
Autores principales: Qu, Shiqiang, Yan, Yiru, Li, Chengwen, Xu, Zefeng, Cai, Wenyu, Qin, Tiejun, Zhang, Peihong, Jia, Yujiao, Pan, Lijuan, Gao, Qingyan, Li, Bing, Liu, Jinqin, Jiao, Meng, Xiao, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036931/
https://www.ncbi.nlm.nih.gov/pubmed/36968263
http://dx.doi.org/10.1016/j.lrr.2023.100367