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Regorafenib induces NOX5-mediated endoplasmic reticulum stress and potentiates the anti-tumor activity of cisplatin in non-small cell lung cancer cells

Lung cancer is one of the most commonly diagnosed cancers worldwide. Although cisplatin-based chemotherapy regimens serve a pivotal role in non-small cell lung cancer (NSCLC) treatment, drug resistance and serious side effects limited its further clinical application. Regorafenib, a small-molecule m...

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Detalles Bibliográficos
Autores principales: Sui, Hehuan, Xiao, Sisi, Jiang, Suping, Wu, Siyuan, Lin, Haizhen, Cheng, Liyuan, Ye, Lihua, Zhao, Qi, Yu, Yun, Tao, Lu, Kong, Feng-Ming, Huang, Xiaoying, Cui, Ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036942/
https://www.ncbi.nlm.nih.gov/pubmed/36940556
http://dx.doi.org/10.1016/j.neo.2023.100897