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A pan-cancer landscape of centromere proteins in tumorigenesis and anticancer drug sensitivity
BACKGROUND: During mitosis and meiosis, centromere proteins (CENPs) play a key role in proper chromosome segregation. Abnormal expression of CENPs leads to chromosome instability, which is the main cause of tumorigenesis. METHODS: To elucidate the functional characteristics of CENPs in pan-cancer, w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036944/ https://www.ncbi.nlm.nih.gov/pubmed/36944275 http://dx.doi.org/10.1016/j.tranon.2023.101658 |