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A pan-cancer landscape of centromere proteins in tumorigenesis and anticancer drug sensitivity

BACKGROUND: During mitosis and meiosis, centromere proteins (CENPs) play a key role in proper chromosome segregation. Abnormal expression of CENPs leads to chromosome instability, which is the main cause of tumorigenesis. METHODS: To elucidate the functional characteristics of CENPs in pan-cancer, w...

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Detalles Bibliográficos
Autores principales: Shi, Yuan-Xiang, Dai, Peng-Hui, Jiang, Yu-Fei, Wang, Yan-Qing, Liu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036944/
https://www.ncbi.nlm.nih.gov/pubmed/36944275
http://dx.doi.org/10.1016/j.tranon.2023.101658