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Metformin mitigates radiation toxicity exerting antioxidant and genoprotective properties

The antidiabetic drug metformin (MF) exhibits redox-modulating effects in various pathologies associated with oxidative stress and mitigates ionizing radiation-induced toxicity, but the underlying mechanisms remain to be elucidated. Thus, we studied some radiomitigatory effects of MF and explored th...

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Detalles Bibliográficos
Autores principales: Karmanova, Ekaterina E., Chernikov, Anatoly V., Popova, Nelli R., Sharapov, Mars G., Ivanov, Vladimir E., Bruskov, Vadim I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036983/
https://www.ncbi.nlm.nih.gov/pubmed/36961549
http://dx.doi.org/10.1007/s00210-023-02466-w