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Fitness and Functional Landscapes of the E. coli RNase III Gene rnc

How protein properties such as protein activity and protein essentiality affect the distribution of fitness effects (DFE) of mutations are important questions in protein evolution. Deep mutational scanning studies typically measure the effects of a comprehensive set of mutations on either protein ac...

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Detalles Bibliográficos
Autores principales: Weeks, Ryan, Ostermeier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037077/
https://www.ncbi.nlm.nih.gov/pubmed/36848192
http://dx.doi.org/10.1093/molbev/msad047