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Fitness and Functional Landscapes of the E. coli RNase III Gene rnc
How protein properties such as protein activity and protein essentiality affect the distribution of fitness effects (DFE) of mutations are important questions in protein evolution. Deep mutational scanning studies typically measure the effects of a comprehensive set of mutations on either protein ac...
Autores principales: | Weeks, Ryan, Ostermeier, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037077/ https://www.ncbi.nlm.nih.gov/pubmed/36848192 http://dx.doi.org/10.1093/molbev/msad047 |
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