Quantify permeability using on-a-chip models in high-throughput applications

Traditionally, to quantify permeability of a biological barrier, the initial slope is used, based on the assumption of sink condition (concentration of the donor is constant, and the receiver increases less than 10%). With on-a-chip barrier models, this assumption fails in cell-free or leaky conditi...

Descripción completa

Detalles Bibliográficos
Autores principales: Soragni, Camilla, Vergroesen, Tessa, Hettema, Nynke, Rabussier, Gwenaëlle, Lanz, Henriëtte L., Trietsch, Sebastian J., de Windt, Leon J., Ng, Chee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037215/
https://www.ncbi.nlm.nih.gov/pubmed/36861838
http://dx.doi.org/10.1016/j.xpro.2023.102051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037215/
https://www.ncbi.nlm.nih.gov/pubmed/36861838
http://dx.doi.org/10.1016/j.xpro.2023.102051

Ejemplares similares