Cargando…
Molecular mechanisms of mitochondrial DNA release and activation of the cGAS-STING pathway
In addition to constituting the genetic material of an organism, DNA is a tracer for the recognition of foreign pathogens and a trigger of the innate immune system. cGAS functions as a sensor of double-stranded DNA fragments and initiates an immune response via the adaptor protein STING. The cGAS-ST...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037406/ https://www.ncbi.nlm.nih.gov/pubmed/36964253 http://dx.doi.org/10.1038/s12276-023-00965-7 |