Total Synthesis of Hemerocallisamine I Paved by Gram-Scale Synthesis of (2S,4S)-4-Hydroxyglutamic Acid Lactone

Total synthesis of the 2-formylpyrrole alkaloid hemerocallisamine I is presented, both in racemic and enantiopure form. Our synthetic strategy involves (2S,4S)-4-hydroxyglutamic acid lactone as the key intermediate. Starting from an achiral substrate, the target stereogenic centers were introduced b...

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Detalles Bibliográficos
Autores principales: Pinčeková, Lucia, Jančiová, Eva, Berkeš, Dušan, Gyepes, Róbert, Kolarovič, Andrej, Caletková, Oľga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037412/
https://www.ncbi.nlm.nih.gov/pubmed/36903423
http://dx.doi.org/10.3390/molecules28052177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037412/
https://www.ncbi.nlm.nih.gov/pubmed/36903423
http://dx.doi.org/10.3390/molecules28052177

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