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Modular Chemical Construction of IgG-like Mono- and Bispecific Synthetic Antibodies (SynAbs)

[Image: see text] In recent years there has been rising interest in the field of protein–protein conjugation, especially related to bispecific antibodies (bsAbs) and their therapeutic applications. These constructs contain two paratopes capable of binding two distinct epitopes on target molecules an...

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Detalles Bibliográficos
Autores principales: Thoreau, Fabien, Szijj, Peter A., Greene, Michelle K., Rochet, Léa N. C., Thanasi, Ioanna A., Blayney, Jaine K., Maruani, Antoine, Baker, James R., Scott, Christopher J., Chudasama, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037451/
https://www.ncbi.nlm.nih.gov/pubmed/36968530
http://dx.doi.org/10.1021/acscentsci.2c01437