Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time

[Image: see text] Variable-temperature electrospray ionization (vT-ESI) native mass spectrometry (nMS) is used to determine the thermodynamics for stepwise binding of up to 14 ATP molecules to the 801 kDa GroEL tetradecamer chaperonin complex. Detailed analysis reveals strong enthalpy–entropy compen...

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Detalles Bibliográficos
Autores principales: Walker, Thomas, Sun, He Mirabel, Gunnels, Tiffany, Wysocki, Vicki, Laganowsky, Arthur, Rye, Hays, Russell, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037461/
https://www.ncbi.nlm.nih.gov/pubmed/36968544
http://dx.doi.org/10.1021/acscentsci.2c01065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037461/
https://www.ncbi.nlm.nih.gov/pubmed/36968544
http://dx.doi.org/10.1021/acscentsci.2c01065

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