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Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time
[Image: see text] Variable-temperature electrospray ionization (vT-ESI) native mass spectrometry (nMS) is used to determine the thermodynamics for stepwise binding of up to 14 ATP molecules to the 801 kDa GroEL tetradecamer chaperonin complex. Detailed analysis reveals strong enthalpy–entropy compen...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037461/ https://www.ncbi.nlm.nih.gov/pubmed/36968544 http://dx.doi.org/10.1021/acscentsci.2c01065 |