Chemical Knockdown of Phosphorylated p38 Mitogen-Activated Protein Kinase (MAPK) as a Novel Approach for the Treatment of Alzheimer′s Disease

[Image: see text] Targeted protein degradation (TPD) provides unique advantages over gene knockdown in that it can induce selective degradation of disease-associated proteins attributed to pathological mutations or aberrant post-translational modifications (PTMs). Herein, we report a protein degrade...

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Detalles Bibliográficos
Autores principales: Son, Seung Hwan, Lee, Na-Rae, Gee, Min Sung, Song, Chae Won, Lee, Soo Jin, Lee, Sang-Kyung, Lee, Yoonji, Kim, Hee Jin, Lee, Jong Kil, Inn, Kyung-Soo, Kim, Nam-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037464/
https://www.ncbi.nlm.nih.gov/pubmed/36968534
http://dx.doi.org/10.1021/acscentsci.2c01369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037464/
https://www.ncbi.nlm.nih.gov/pubmed/36968534
http://dx.doi.org/10.1021/acscentsci.2c01369

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