Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury

[Image: see text] Soluble epoxide hydrolase (sEH) plays a critical role in inflammation by modulating levels of epoxyeicosatrienoic acids (EETs) and other epoxy fatty acids (EpFAs). Here, we investigate the possible role of sEH in lipopolysaccharide (LPS)-mediated macrophage activation and acute lun...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Zhang, Min, Huo, Xiao-Kui, Ning, Jing, Yu, Zhen-Long, Morisseau, Christophe, Sun, Cheng-Peng, Hammock, Bruce D., Ma, Xiao-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037491/
https://www.ncbi.nlm.nih.gov/pubmed/36968547
http://dx.doi.org/10.1021/acscentsci.2c01424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037491/
https://www.ncbi.nlm.nih.gov/pubmed/36968547
http://dx.doi.org/10.1021/acscentsci.2c01424

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