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Sulfonylation of RNA 2′-OH groups

[Image: see text] The nucleophilic reactivity of RNA 2′-OH groups in water has proven broadly useful in probing, labeling, and conjugating RNA. To date, reactions selective to ribose 2′-OH have been limited to bond formation with short-lived carbonyl electrophiles. Here we report that many activated...

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Detalles Bibliográficos
Autores principales: Chatterjee, Sayantan, Shioi, Ryuta, Kool, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037496/
https://www.ncbi.nlm.nih.gov/pubmed/36968531
http://dx.doi.org/10.1021/acscentsci.2c01237