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MgIG Attenuates Oxaliplatin-induced Hepatotoxicity through Suppression of Connexin 43 in Hepatic Stellate Cells

BACKGROUND AND AIMS: Oxaliplatin is widely used in cancer chemotherapy with adverse effects such as liver toxicity. Magnesium isoglycyrrhizinate (MgIG) has hepatoprotective effects, but the underlying mechanism remains elusive. The study’s aim was to investigate the mechanism underlying the hepatopr...

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Detalles Bibliográficos
Autores principales: Cao, Yuzhu, Xia, Yawen, Wang, Yufei, Shi, Hang, Wu, Yuanyuan, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037507/
https://www.ncbi.nlm.nih.gov/pubmed/36969904
http://dx.doi.org/10.14218/JCTH.2022.00048