Therapeutic Effects of WT1 Silencing via Respiratory Administration of Neutral DOPC Liposomal-siRNA in a Lung Metastasis Melanoma Murine Model

The lungs represent a frequent target for metastatic melanoma as they offer a high-oxygen environment for tumor development. The overexpression of the WT1 protein has been associated with the occurrence of melanoma. In this study, we evaluated the effects of silencing the WT1 protein by siRNA in bot...

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Detalles Bibliográficos
Autores principales: Ramos-Gonzalez, Martin R., Vazquez-Garza, Eduardo, Garcia-Rivas, Gerardo, Rodriguez-Aguayo, Cristian, Chavez-Reyes, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037624/
https://www.ncbi.nlm.nih.gov/pubmed/36960966
http://dx.doi.org/10.3390/ncrna9020021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037624/
https://www.ncbi.nlm.nih.gov/pubmed/36960966
http://dx.doi.org/10.3390/ncrna9020021

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