PES1 reduces CD8(+) T cell infiltration and immunotherapy sensitivity via interrupting ILF3-IL15 complex in esophageal squamous cell carcinoma

BACKGROUND: Although immune checkpoint blockade (ICB) therapy has brought survival benefits to patients with specific cancer types, most of cancer patients remain refractory to the ICB therapy, which is largely attributed to the immunosuppressive tumor microenvironment. Thereby, it is urgent to prof...

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Detalles Bibliográficos
Autores principales: Ma, Ning, Hua, Rong, Yang, Yang, Liu, Zhi-Chao, Pan, Jie, Yu, Bo-Yao, Sun, Yi-Feng, Xie, Dong, Wang, Yan, Li, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037800/
https://www.ncbi.nlm.nih.gov/pubmed/36959575
http://dx.doi.org/10.1186/s12929-023-00912-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037800/
https://www.ncbi.nlm.nih.gov/pubmed/36959575
http://dx.doi.org/10.1186/s12929-023-00912-8

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