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Metformin regulates expression of DNA methyltransferases through the miR-148/-152 family in non-small lung cancer cells

BACKGROUND: To understand the molecular mechanisms involved in regulation of DNA methyltransferases (DNMTs) by metformin in non-small cell lung cancer (NSCLC) cells. METHODS: Expression levels of DNMTs in response to metformin were analyzed in NSCLC cells. MicroRNAs regulating expression of DNMTs at...

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Detalles Bibliográficos
Autores principales: Lee, Bo Bin, Kim, Dongho, Kim, Yujin, Han, Joungho, Shim, Young Mog, Kim, Duk-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037810/
https://www.ncbi.nlm.nih.gov/pubmed/36959680
http://dx.doi.org/10.1186/s13148-023-01466-0