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GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity
BACKGROUND: The severe unfavorable effects of doxorubicin on the heart restrict its clinical usage. Numerous investigations document that cyclic GMP-AMP synthase (cGAS) activator of interferon genes (STING) cascade influences inflammation along with the immune response in a variety of diseases. The...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037834/ https://www.ncbi.nlm.nih.gov/pubmed/36964634 http://dx.doi.org/10.1186/s40360-022-00631-0 |