Cargando…
GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity
BACKGROUND: The severe unfavorable effects of doxorubicin on the heart restrict its clinical usage. Numerous investigations document that cyclic GMP-AMP synthase (cGAS) activator of interferon genes (STING) cascade influences inflammation along with the immune response in a variety of diseases. The...
Autores principales: | Xiao, Zilong, Yu, Ziqing, Chen, Chaofeng, Chen, Ruizhen, Su, Yangang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037834/ https://www.ncbi.nlm.nih.gov/pubmed/36964634 http://dx.doi.org/10.1186/s40360-022-00631-0 |
Ejemplares similares
-
The Essential Strategies to Mitigate Cardiotoxicity Caused by Doxorubicin
por: Chaulin, Aleksey Michailovich
Publicado: (2023) -
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity
por: Tadokoro, Tomonori, et al.
Publicado: (2023) -
What role of the cGAS-STING pathway plays in chronic pain?
por: Wu, Jingxiang, et al.
Publicado: (2022) -
The role of cGAS-STING signalling in liver diseases
por: Chen, Ruihan, et al.
Publicado: (2021) -
Trimetazidine Affects Mitochondrial Calcium Uniporter Expression to Restore Ischemic Heart Function via Reactive Oxygen Species/NFκB Pathway Inhibition
por: Xiao, Zilong, et al.
Publicado: (2023)