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GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity

BACKGROUND: The severe unfavorable effects of doxorubicin on the heart restrict its clinical usage. Numerous investigations document that cyclic GMP-AMP synthase (cGAS) activator of interferon genes (STING) cascade influences inflammation along with the immune response in a variety of diseases. The...

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Detalles Bibliográficos
Autores principales: Xiao, Zilong, Yu, Ziqing, Chen, Chaofeng, Chen, Ruizhen, Su, Yangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037834/
https://www.ncbi.nlm.nih.gov/pubmed/36964634
http://dx.doi.org/10.1186/s40360-022-00631-0

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