Generation of robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds: a comprehensive comparison of formats

Bispecific antibodies (bsAbs) enable dual binding of different antigens with potential synergistic targeting effects and innovative therapeutic possibilities. The formation of bsAbs is, however, often dependent on complex engineering strategies with a high risk of antibody chain mispairing leading t...

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Detalles Bibliográficos
Autores principales: Madsen, Andreas V., Kristensen, Peter, Buell, Alexander K., Goletz, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038023/
https://www.ncbi.nlm.nih.gov/pubmed/36939220
http://dx.doi.org/10.1080/19420862.2023.2189432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038023/
https://www.ncbi.nlm.nih.gov/pubmed/36939220
http://dx.doi.org/10.1080/19420862.2023.2189432

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