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Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues

Prions are infectious protein particles known to cause prion diseases. The biochemical entity of the pathogen is the misfolded prion protein (PrP(Sc)) that forms insoluble amyloids to impair brain function. PrP(Sc) interacts with the non-pathogenic, cellular prion protein (PrP(C)) and facilitates co...

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Detalles Bibliográficos
Autores principales:	Kim, Dong Hwan, Kim, Jaehyeon, Lee, Hakmin, Lee, Dongyun, Im, So Myoung, Kim, Ye Eun, Yoo, Miryeong, Cheon, Yong-Pil, Bartz, Jason C., Son, Young-Jin, Choi, Eun-Kyoung, Kim, Yong-Sun, Jeon, Jae-Ho, Kim, Hyo Shin, Lee, Sungeun, Ryou, Chongsuk, Nam, Tae-gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038035/ https://www.ncbi.nlm.nih.gov/pubmed/36950944 http://dx.doi.org/10.1080/14756366.2023.2191164

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