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In vivo DNA methylation editing in zebrafish

The CRISPR/dCas9-based epigenome editing technique has driven much attention. Fused with a catalytic domain from Dnmt or Tet protein, the CRISPR/dCas9-DnmtCD or -TetCD systems possess the targeted DNA methylation editing ability and have established a series of in vitro and in vivo disease models. H...

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Detalles Bibliográficos
Autores principales: Liang, Fang, Dong, Zijiong, Ye, Jianmin, Hu, Wei, Bhandari, Ramji Kumar, Mai, Kangsen, Wang, Xuegeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038036/
https://www.ncbi.nlm.nih.gov/pubmed/36945831
http://dx.doi.org/10.1080/15592294.2023.2192326