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CD25(bright) NK cells display superior function and metabolic activity under regulatory T cell-mediated suppression

Infusion of natural killer (NK) cells is an attractive therapeutic modality in patients with cancer. However, the activity of NK cells is regulated by several mechanisms operating within solid tumors. Regulatory T (Treg) cells suppress NK cell activity through various mechanisms including deprivatio...

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Detalles Bibliográficos
Autores principales: Chen, Ziqing, Tong, Le, Neo, Shi Yong, Li, Shuijie, Gao, Jiwei, Schlisio, Susanne, Lundqvist, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038043/
https://www.ncbi.nlm.nih.gov/pubmed/36970070
http://dx.doi.org/10.1080/2162402X.2023.2175517