Cargando…

CD25(bright) NK cells display superior function and metabolic activity under regulatory T cell-mediated suppression

Infusion of natural killer (NK) cells is an attractive therapeutic modality in patients with cancer. However, the activity of NK cells is regulated by several mechanisms operating within solid tumors. Regulatory T (Treg) cells suppress NK cell activity through various mechanisms including deprivatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ziqing, Tong, Le, Neo, Shi Yong, Li, Shuijie, Gao, Jiwei, Schlisio, Susanne, Lundqvist, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038043/ https://www.ncbi.nlm.nih.gov/pubmed/36970070 http://dx.doi.org/10.1080/2162402X.2023.2175517

Ejemplares similares

Phosphodiesterase 4A confers resistance to PGE2‐mediated suppression in CD25(+)/CD54(+) NK cells
por: Chen, Ziqing, et al.
Publicado: (2021)

Strategies to Augment Natural Killer (NK) Cell Activity against Solid Tumors
por: Chen, Ziqing, et al.
Publicado: (2019)

Ribavirin Does Not Impair the Suppressive Activity of Foxp3(+)CD4(+)CD25(+) Regulatory T Cells
por: Lee, Jeewon, et al.
Publicado: (2013)

Tumor MHC class I expression alters cancer-associated myelopoiesis driven by host NK cells
por: Neo, Shi Yong, et al.
Publicado: (2022)

Single-cell profiling reveals periventricular CD56(bright) NK cell accumulation in multiple sclerosis
por: Rodríguez-Lorenzo, Sabela, et al.
Publicado: (2022)

NK cells in COVID-19: protectors or opponents?
por: Alrubayyi, Aljawharah
Publicado: (2020)

ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway
por: Huang, Wen-Kuan, et al.
Publicado: (2021)

Reduction of the CD16(−)CD56(bright) NK Cell Subset Precedes NK Cell Dysfunction in Prostate Cancer
por: Koo, Kyo Chul, et al.
Publicado: (2013)

Human Hepatic CD56(bright) NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8(+) T Cells
por: Jameson, Gráinne, et al.
Publicado: (2022)

The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56(bright) NK cells
por: Ziegler, Annerose E., et al.
Publicado: (2023)

Renal cell carcinoma escapes NK cell‐mediated immune surveillance through the downregulation of DNAM‐1
por: Tong, Le, et al.
Publicado: (2023)

CD4(+)CD25(+)Foxp3(+) regulatory T cells suppress NKG2D-mediated NK cell cytotoxicity in peripheral blood
por: Geng, Xu, et al.
Publicado: (2019)

CD25(bright)CD4(+ )regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
por: Cao, Duojia, et al.
Publicado: (2004)

The Role of CD4(+)CD25(bright) Regulatory T Cells in the Maintenance of Pregnancy, Premature Rupture of Membranes, and Labor
por: Seol, Hyun-Joo, et al.
Publicado: (2008)

CD25brightCD4(+ )regulatory T cells accumulate in inflamed joints of patients with chronic rheumatic disease
por: Cao, D, et al.
Publicado: (2004)

Human Cd25(+)Cd4(+) T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function
por: Levings, Megan K., et al.
Publicado: (2001)

PILRα binds an unknown receptor expressed primarily on CD56(bright) and decidual-NK cells and activates NK cell functions
por: Ophir, Yael, et al.
Publicado: (2016)

Ex Vivo Isolation and Characterization of Cd4(+)Cd25(+) T Cells with Regulatory Properties from Human Blood
por: Dieckmann, Detlef, et al.
Publicado: (2001)

Ageing is associated with a decline in peripheral blood CD56(bright )NK cells
por: Chidrawar, Shivani M, et al.
Publicado: (2006)

Circulating CD56(bright) NK cells inversely correlate with survival of melanoma patients
por: de Jonge, Kaat, et al.
Publicado: (2019)

Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates
por: Malengier-Devlies, Bert, et al.
Publicado: (2022)

NK Cell Induced T Cell Anergy Depends on GRAIL Expression
por: Galazka, Grazyna, et al.
Publicado: (2019)

Regulatory NK cells in autoimmune disease
por: Bahadorian, Davood, et al.
Publicado: (2023)

Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer
por: Sarhan, Dhifaf, et al.
Publicado: (2022)

The Increased Ratio of Blood CD56(bright) NK to CD56(dim) NK Is a Distinguishing Feature of Primary Sjögren's Syndrome
por: Ming, Bingxia, et al.
Publicado: (2020)

Extranodal NK/T-Cell Lymphoma Mimicking an Infectious Granuloma
por: Suh, Min Song, et al.
Publicado: (2019)

NK cells and solid tumors: therapeutic potential and persisting obstacles
por: Tong, Le, et al.
Publicado: (2022)

Electrochromic Inorganic Nanostructures with High Chromaticity and Superior Brightness
por: Gugole, Marika, et al.
Publicado: (2021)

Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
por: Krammer, Susanne, et al.
Publicado: (2022)

Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells
por: Nishikawa, Hiroyoshi, et al.
Publicado: (2005)

Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus
por: Vermeulen, Ben L., et al.
Publicado: (2013)

Brightness Prediction of Large Color Gamut Laser Display Devices
por: Zhu, Jianying, et al.
Publicado: (2023)

The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation
por: Rossi, Gustavo R., et al.
Publicado: (2020)

Regulatory effects of dexamethasone on NK and T cell immunity
por: Chen, Liying, et al.
Publicado: (2017)

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4(+) T lymphocytes by CD4(+) CD25(+) regulatory T cells
por: Bopp, Tobias, et al.
Publicado: (2005)

Acquisition of cell migration defines NK cell differentiation from hematopoietic stem cell precursors
por: Lee, Barclay J., et al.
Publicado: (2017)

Toll‐like receptor 2(bright) cells identify circulating monocytes in human and non‐human primates
por: Shirk, Erin N., et al.
Publicado: (2017)

FcRγ Gene Editing Reprograms Conventional NK Cells to Display Key Features of Adaptive Human NK Cells
por: Liu, Weiru, et al.
Publicado: (2020)

Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection
por: Min-Oo, Gundula, et al.
Publicado: (2014)

Serum HBV pregenomic RNA exhibited opposite associations with NK(dim) and NK(bright) cell immunity in treatment-naïve chronic hepatitis B patients
por: Gu, Yurong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8sjnpuoj5ia8o097sopdl65q2p