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Inhibition of Integrin α(v)β(3)-FAK-MAPK signaling constrains the invasion of T-ALL cells

The role of adhesion receptor integrin αvβ3 in T-ALL was unclear. Firstly, we performed quantitative real-time PCR to assess medullary expression of integrin β3(ITGB3) in T-ALL patients and high ITGB3 expression was relevant with the central nervous system leukemia(CNSL) incidence. Decreasing of cel...

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Detalles Bibliográficos
Autores principales: Huang, Lan, Zhu, Yao, Kong, Qinglin, Guan, Xianmin, Lei, Xiaoying, Zhang, Luying, Yang, Hui, Yao, Xinyuan, Liang, Shaoyan, An, Xizhou, Yu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038045/
https://www.ncbi.nlm.nih.gov/pubmed/36944577
http://dx.doi.org/10.1080/19336918.2023.2191913