Crohn’s disease-associated AIEC inhibiting intestinal epithelial cell-derived exosomal let-7b expression regulates macrophage polarization to exacerbate intestinal fibrosis

The interaction between adherent-invasive Escherichia coli (AIEC) and intestinal macrophages is implicated in the pathogenesis of Crohn’s disease (CD). However, its role in intestinal fibrogenesis and the underlying molecular mechanisms are poorly understood. In addition, miRNAs such as let-7b may p...

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Detalles Bibliográficos
Autores principales: Xu, Yihan, Qian, Wenwei, Huang, Liangyu, Wen, Weiwei, Li, Yi, Guo, Feilong, Zhu, Zhenxing, Li, Zhun, Gong, Jianfeng, Yu, Zeqian, Zhou, Yan, Lu, Nan, Zhu, Weiming, Guo, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038049/
https://www.ncbi.nlm.nih.gov/pubmed/36945126
http://dx.doi.org/10.1080/19490976.2023.2193115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038049/
https://www.ncbi.nlm.nih.gov/pubmed/36945126
http://dx.doi.org/10.1080/19490976.2023.2193115

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