Impact of IgG subclass on monoclonal antibody developability

IgG-based monoclonal antibody therapeutics, which are mainly IgG1, IgG2, and IgG4 subclasses or related variants, have dominated the biotherapeutics field for decades. Multiple laboratories have reported that the IgG subclasses possess different molecular characteristics that can affect their develo...

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Detalles Bibliográficos
Autores principales: Cain, Paul, Huang, Lihua, Tang, Yu, Anguiano, Victor, Feng, Yiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038059/
https://www.ncbi.nlm.nih.gov/pubmed/36945111
http://dx.doi.org/10.1080/19420862.2023.2191302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038059/
https://www.ncbi.nlm.nih.gov/pubmed/36945111
http://dx.doi.org/10.1080/19420862.2023.2191302

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